I have been a diabetic for 4 years. This is the first serum that I have ever used in my life. I always use lotions - creams but most of them irritate more than help my dry itchy skin. My arms & legs have itched to the point of me scratching until sometimes I would bleed. Nothing I tried would stop the itching for long. I applied this serum and immediately I felt a huge sigh of relief as my skin was soothed & calmed. I cannot overstate how very pleased I am with how amazingly good my skin looks!