Genitourinary system

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Renal, metabolic and cardiovascular considerations of SGLT2 inhibition Genitourinary System, Insulin Sensitivity, High Cholesterol Levels, Blood Glucose Levels, Glucose Levels, Ldl Cholesterol, Circulatory System, Nursing Student, Cardiovascular Disease

The kidney has a key role in maintaining glucose homeostasis and is the site of action of SGLT2 inhibitors, which enhance glucose excretion to reduce plasma glucose levels. Here, Ralph DeFronzo and colleagues examine the role of the kidney in regulating glucose reabsorption and the effect of SGLT2 inhibition on renal function, glucose homeostasis, and cardiovascular disease.

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diagram of the structure of an urne

Explain the Mechanism of Urine Formation Mechanism of Urine Formation It has four steps – ultra filtration, selective reabsorption, secretion and concentration. (i) Ultra Filtration. Blood flows inside glomerulus under pressure due to narrowness of efferent arteriole. As a result it undergoes pressure filtration or ultrafiltration. All small volume solutes (e.g., urea, uric acid, amino […]

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