Origin and differentiation of immune system cells The human immunological system comprises several organs including the spleen, thymus, lymph nodes and bone marrow, each contributing to the development of immune cells. Shown above is a nice overview of these immune cells in terms of the stem cell origin and subsequent differentiation.
Erythropoiesis- Red Blood Cell (RBC) Creation. This dynamic process primarily occurs within the bone marrow & is regulated by the renal hormonal release of erythropoietin (EPO) in response to low oxygen levels.
Thank Goodness for B-Cells! B-Cells are a type of white blood cell within the lymphocyte category. They play a crucial role in immune function by fighting off trespassing invaders such as viruses. Upon contact with a pathogen, it records the unique microbial shape & creates a specialized protein structure, or antibody, to disable the foreign intruder upon subsequent exposure. This is why we don’t contract illness from a cold or flu virus more than once.
"Like a Best Friend to Immunity."T Helper-Cells are a type of white blood cell that is within the lymphocyte category. They are pegged as “helpers” due to their role in assisting B-cell activation, along with the support of other immune mediated cells. T-Cells are primed for battle upon exposure to certain pathogens that express a MHC-II protein on their membrane surface. Once triggered, the rapidly divide & secrete cytokines, small proteins that initiate assorted immune responses.
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