Vito 'Don Vito' Cascioferro, former Sicilian Boss of Bosses. Speculation is he sent Salvatore Maranzano to America in order to setup the mafia there. He was responsible for establishing the strong connection that still exists between the Sicilian and American Mafias. He died in Sicilian prison.
Sammy the Bull. Originally a mobster for the Colombo crime family, and later for the Brooklyn faction of the Gambinos, Gravano participated in the conspiracy to murder Gambino boss Paul Castellano. He played a key role in planning and executing Castellano's murder. After Castellano's death, Gotti elevated Gravano to underboss. At the time, Gravano was the highest ranking member of the Five Families to break his Cosa Nostra oath and cooperate with the government.
Albert Anastasia (pronounced ah-nah-STAH-zee-ah) (born Umberto Anastasio, September 26, 1902 – October 25, 1957) was one of the most ruthless and feared Cosa Nostra mobsters in U. S. history. A founder of the American Mafia, Anastasia ran Murder, Inc. during the prewar era and was boss of the modern Gambino crime family during most of the 1950s.
Giuseppe "Joe" Profaci: (Sicily, October 2 1897– Queens, June 7 1962) was a New York La Cosa Nostra boss who was the founder of what is today known as the Colombo crime family. Established in 1928, this was the last of the Five Families to be organized. He was the family's boss for over three decades.